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Chronic Fatigue Syndrome
The Chronic Fatigue Syndrome (CFS) is characterised by the sudden
onset of an infectious-type illness, the subsequent chronic and
debilitating fatigue, and postexertional malaise; many patients
also have recurrent fevers, pharyngitis, adenopathy, myalgias, sleep
disorders, and cognitive impairment. Up to 70% of patients with
CFS complain of sleep disruption and unrefreshing sleep. This has
now been objectively demonstrated through the use of Polysomnogram
sleep studies that have demonstrated decreased sleep efficiency
and intrusion of the wakeful state into deep sleep in a significant
proportion of these patients. There is some evidence that patients
with CFS have a deficit in slow Wave sleep called the alpha-delta
phenomenon.
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